Research & Publications


We are an active member of the ANZICS Clinical Trials Group. We have participated in a number of studies including RENAL, MET and LUNGSAFE for the ESICM


The RENAL Replacement Therapy Study Investigators. Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients.N Engl J Med 2009; 361:1627-1638.

RENAL Replacement Therapy study Investigators, Bellomo R, et al.An observational study fluid balance and patient outcomes in the Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy trialCrit Care Med. 2012 Jun;40(6):1753-60.

Bellani et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. February 23, 2016, Vol 315, No. 8.

Laffey et al, LUNG SAFE Investigators and the ESICM Trials Group. Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study. Intensive Care Med. 2016 Dec;42(12):1865-1876.

Psirides A. J. , Hill J,  Jones D.Rapid Response Team activation in New Zealand hospitals—a multicentre prospective observational study. Anaesth Intensive Care 2016 | 44:3


Manara A R, Thomas I, Harding R.A case for stopping the early withdrawal
of life sustaining therapies in patients with devastating brain injuries. JICS 2016:0(0)

Moore LSP, Owens, DS, Jepson A, Turton J, Ashworth S, Donaldson H, Holmes A. Waterborne Elizabethkingia meningoseptica in adult critical care: an analysis of an outbreak and the organism’s role as an emerging nosocomial pathogen.Emerging Infectious Diseases. 2016:22(1)

Meyer E. ‘A review of renal protection strategies’ South Afr J Anaesth Analg. 2015:21(2):5-8

Jeyanathan J & Owens D ‘Objective Structured Clinical Examination in Intensive Care Medicine’ TFM publishing ltd. July 2015

Kalkoff M, Sleigh J, Cursons R, Bertinelli A, Jogia P, La Pine M, Richards M, Towers R, Devlin, Alpha-1 adrenergic receptor mRNA expression in circulating leucocytes after cardiac surgery, Anaesth and Intensive CareVol 2008 36(4); p535-543

Jogia P, Kalkoff M, JW Sleigh, A. Bertinelli , La Pine M, AM Richards, G.Delvin. NT-pro BNP secretion and clinical endpoints in cardiac surgery intensive care patients. Anaesth Int Care. 2007; 35:363-369

Kalkoff M, Cursons RT, Sleigh JW, Jacobson GM.The use of real time rtPCR to quantify inflammatory mediator expression in leukocytes from patients with severe sepsis. Anaesth Intensive Care. 2004 Dec; 32(6): 746-55.

Ireland N, Kalkoff M, Cursons RT, Sleigh JW.  Messenger RNA expression of multiple immune mediators in leukocytes from elective orthopaedic surgical patients.  Anaesth Intensive Care.  2004: 32(2); 188-195.